Hormone Leptin, is one of the hormones responsible, it is secreted by adipose cells in response to an increase in body fat mass, it acts as a ;Fat-o-Stat' it sends messages to the brain.
When Leptin levels rise in the blood, its sending message to the brain to do a few things, one of which: suppress the release of NPY which is the mose potent appetite stimulant known - Neuropeptide Y.
By blocking its release, leptin pevents the release of the appetite-enhancing hormones. This decreases appetite and subsequently food intake, eventually promoting weight loss.
When 'fat stores' shrink, leptin blood levels drop, activating receptors in the brain, releasing hormones, consequently, appetite and food intake increase and eventually weight gain occurs.
Rising Leptin levels do promote weight loss, but only to a certain point.
Individuals who are obese have higher than normal Leptin blood levels, but are resistant to its actions, for some unknown reason.
Leptin has received the most attention as a long term appetite and metabolism regulator, but Insulin acts on NPY release in same way
Reference: Human Anatomy & Physiology, Marieb, Hoen, 8th Ed
When Leptin levels rise in the blood, its sending message to the brain to do a few things, one of which: suppress the release of NPY which is the mose potent appetite stimulant known - Neuropeptide Y.
By blocking its release, leptin pevents the release of the appetite-enhancing hormones. This decreases appetite and subsequently food intake, eventually promoting weight loss.
When 'fat stores' shrink, leptin blood levels drop, activating receptors in the brain, releasing hormones, consequently, appetite and food intake increase and eventually weight gain occurs.
Rising Leptin levels do promote weight loss, but only to a certain point.
Individuals who are obese have higher than normal Leptin blood levels, but are resistant to its actions, for some unknown reason.
Leptin has received the most attention as a long term appetite and metabolism regulator, but Insulin acts on NPY release in same way
Reference: Human Anatomy & Physiology, Marieb, Hoen, 8th Ed
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